Apoptosis

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:A Review of Programmed Cell Death

Thisis a journal article that mainly focuses on the aspect of apoptosis.The term apoptosis is used to mean a process through cell death isprogrammed. The author of this journal tries to incorporate allprocesses including the background of this process and the severalstages that make up the process. At some point, the author includesother non-apoptotic forms. The author of this article takes much ofthe time to explain the aspect of the study of the cellcharacteristics and more so their mechanisms. Morphology is,therefore, important as the stage of cell development and the shapeis critical in the programmed cell death. The biochemicalcharacteristics of this process are also well covered in the journal.

Mitochondrialapoptosis: killing cancer using the enemy within.

Thisis the second article that concerns itself with the aspect of cancertreatment. To be specific, there is the aspect of mitochondrialapoptosis. As a matter of fact, the author points out how theprogrammed cell death is a big contributor to cancer treatment.Cancer treatment can, therefore, be based on the aspect of apoptosisof these cells in the body. Mitochondria are the main target to killcancer cells.

Thorburn,A. (2008, January). and Autophagy

Ontop of apoptosis, this journal article goes a step higher to evaluateautophagy. The author at first focuses on pointing out thesimilarities between the two processes despite them being deemed tobe different. It is evident that the two are core in the developmentof some diseases. It is also pointed out that the two can worksimultaneously. While apoptosis is the death of a cell, autophagy isexplained to be an important process in the death of a cell.

Itis, therefore, evident that in all the texts above, apoptosis isessential especially when it comes to treatment of various diseasesthat affect the cells including cancer. In that cell diseases havebeen found to hinder apoptosis, programmed cell death can overcomethis and aid in the treatment of such.

References

Elmore,S. (2007). : A Review of Programmed Cell Death. RetrievedMarch 25, 2017, fromhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117903/

Lopez,J., &amp Tait, S. W. (2015, March 05). Mitochondrial apoptosis:killing cancer using the enemy within. Retrieved March 25, 2017, fromhttp://www.nature.com/bjc/journal/v112/n6/full/bjc201585a.html

Thorburn,A. (2008, January). and Autophagy: regulatory connectionsbetween two supposedly different processes. Retrieved March 25, 2017,from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2601595/

Apoptosis

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APOPTOSIS 0

InstitutionAffiliation:

Thethree articles present an in-depth analysis and information about. The language used in the articles is easy to understandand have used a limited number of scientific jargons that enableseven those with no scientific knowledge and background to understandthe literature. Moreover, the authors of the three great literaturesof have a wealth of experience in the scientificdiscipline, and their competency is unrivaled. They possess vastexperience and have proven their skills through difficult academicpaths that they have followed. Also, the dedication they have toscience as a subject and they are credited by a higher institution oflearning. Besides the competencies of the authors of the articles,the content is specific and focuses or specializes on the .

Thefirst piece by Elmore (2007), for instance, addresses the subjectobjectively that starts from the basic definition of the broadaspects. It notes how it impacts the health, biochemistry, morphologyand methods that can be detected. All that information isan in-depth worth consulting and review. The second piece by the KhanAcademy (2017) compares and Necrosis and notes thedifference between the two. It explains how occurssystematically and the entire process termed as ‘programmed celldeath.’ The comparison between the two enables readers to get adeeper knowledge of the subject and a better understanding as theycan compare and contrast including the conditions and circumstancethat the two occurs. Lastly, the piece by Samarasinghe (2013) noteshow all cancer cells acquire resistance to . It presentsthe principles that cancer has that present a challenge to the process. The piece, hence, enables readers to further digdeep in knowledge by relating it to a disease and apply the knowledgeearlier read. It also presents the systematic, simple but organizedprocess that works.

Questions

Ifthe elimination of the cells is genetically determined does it meanthere is no cure for one having a problem with the healthissue? What are the similarities and differences between the and Necrosis? What process is involved for cancer cells toacquire resistance to apoptosis?

References

Elmore,S. (2007, December 6). : A Review of Programmed Cell Death[Web log comment]. Retrieved fromhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117903/

KhanAcademy (2017). .Retrieved fromhttps://www.khanacademy.org/science/biology/developmental-biology/apoptosis-in-development/a/apoptosis

Samarasinghe,B. (2013, October 2). Hallmarks of Cancer 3: Evading [Weblog comment]. Retrieved fromhttps://blogs.scientificamerican.com/guest-blog/hallmarks-of-cancer-3-evading-apoptosis/